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Cheap flights from Cartagena to Santo Domingo

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Compare Cartagena to Santo Domingo flight deals

Find the cheapest month or even day of the year to fly to Santo Domingo

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Flight deals from Cartagena to Santo Domingo

Looking for a cheap last-minute deal or the best round-trip flight from Cartagena to Santo Domingo? Find the lowest prices on one-way and round-trip tickets right here.
Santo Domingo.C$377 per passenger.Departing Sun, Jun 8, returning Sun, Jun 15.Round-trip flight with Arajet.Outbound direct flight with Arajet departing from Cartagena on Sun, Jun 8, arriving in Santo Domingo Las Americas.Inbound direct flight with Arajet departing from Santo Domingo Las Americas on Sun, Jun 15, arriving in Cartagena.Price includes taxes and charges.From C$377, select.
Santo Domingo.C$377 per passenger.Departing Thu, Oct 23, returning Sun, Oct 26.Round-trip flight with Arajet.Outbound direct flight with Arajet departing from Cartagena on Thu, Oct 23, arriving in Santo Domingo Las Americas.Inbound direct flight with Arajet departing from Santo Domingo Las Americas on Sun, Oct 26, arriving in Cartagena.Price includes taxes and charges.From C$377, select.
Santo Domingo.C$377 per passenger.Departing Sun, Aug 3, returning Sun, Aug 10.Round-trip flight with Arajet.Outbound direct flight with Arajet departing from Cartagena on Sun, Aug 3, arriving in Santo Domingo Las Americas.Inbound direct flight with Arajet departing from Santo Domingo Las Americas on Sun, Aug 10, arriving in Cartagena.Price includes taxes and charges.From C$377, select.
Santo Domingo.C$383 per passenger.Departing Fri, May 9, returning Mon, May 12.Round-trip flight with Copa.Outbound indirect flight with Copa, departing from Cartagena on Fri, May 9, arriving in Santo Domingo Las Americas.Inbound indirect flight with Copa, departing from Santo Domingo Las Americas on Mon, May 12, arriving in Cartagena.Price includes taxes and charges.From C$383, select.
Santo Domingo.C$384 per passenger.Departing Sun, Feb 8, returning Sun, Feb 15.Round-trip flight with Arajet.Outbound direct flight with Arajet departing from Cartagena on Sun, Feb 8, arriving in Santo Domingo Las Americas.Inbound direct flight with Arajet departing from Santo Domingo Las Americas on Sun, Feb 15, arriving in Cartagena.Price includes taxes and charges.From C$384, select.
Santo Domingo.C$385 per passenger.Departing Tue, May 27, returning Tue, Jun 3.Round-trip flight with Arajet.Outbound direct flight with Arajet departing from Cartagena on Tue, May 27, arriving in Santo Domingo Las Americas.Inbound direct flight with Arajet departing from Santo Domingo Las Americas on Tue, Jun 3, arriving in Cartagena.Price includes taxes and charges.From C$385, select.
Santo Domingo.C$385 per passenger.Departing Sun, May 18, returning Tue, May 20.Round-trip flight with Arajet.Outbound direct flight with Arajet departing from Cartagena on Sun, May 18, arriving in Santo Domingo Las Americas.Inbound direct flight with Arajet departing from Santo Domingo Las Americas on Tue, May 20, arriving in Cartagena.Price includes taxes and charges.From C$385, select.
Santo Domingo.C$400 per passenger.Departing Thu, Sep 18, returning Tue, Sep 23.Round-trip flight with Arajet.Outbound direct flight with Arajet departing from Cartagena on Thu, Sep 18, arriving in Santo Domingo Las Americas.Inbound direct flight with Arajet departing from Santo Domingo Las Americas on Tue, Sep 23, arriving in Cartagena.Price includes taxes and charges.From C$400, select.

When is the cheapest time to fly from Cartagena to Santo Domingo?

We’re always keeping an eye on fares, so you can find the best one in seconds. It looks like Cartagena to Santo Domingo flights are currently cheapest in June.
Apr
Find prices
May
from C$383
Jun
from C$377
Jul
from C$415
Aug
from C$377
Sep
from C$400
Oct
from C$377
Nov
from C$462
Dec
from C$473
Jan
from C$549
Feb
from C$384
Mar
Find prices

Direct flights from Cartagena to Santo Domingo

Alternative Cartagena to Santo Domingo routes

Looking for the cheapest, fastest or easiest route from Cartagena to Santo Domingo? You could fly into the following airports instead.

Cartagena to Santo Domingo: Flight information

The things to know before you go.
Cheapest flight foundC$377
Cheapest month to flyAugust
Average flight time2 hrs, 2 mins
Most popular airlineArajet
Average flights per week5

Finding cheap flights from Cartagena to Santo Domingo: Frequently asked questions

There are 3 airports in Santo Domingo: La Isabela International, Santo Domingo Las Americas and Samana.
The best price we found for a round-trip flight from Cartagena to Santo Domingo is C$377. This is an estimate based on information collected from different airlines and travel providers over the last 4 days and is subject to change and availability.
2 hours and 2 minutes is the average flight time from Cartagena to Santo Domingo.
Arajet flies direct from Cartagena to Santo Domingo.
There are 5 flights per week flying from Cartagena to Santo Domingo, as of April 2025.
The cheapest month to fly from Cartagena to Santo Domingo is usually April 2025.
If you're flying from Cartagena Airport, the cheapest airport near Santo Domingo is Santo Domingo Las Americas – which is 23.4 km away from the center of Santo Domingo. We've found flights to this airport from C$377.
After crunching the numbers on our flight calendar, we found that it's currently cheapest to fly from Cartagena Airport to Santo Domingo on Sunday, August 3, 2025.
Yes – the average flight time is 2 hours and 2 minutes.
We show every price from over 1,200 airlines and travel agents, comparing them all so you don’t have to. If you know you want to fly to Santo Domingo but you’re not ready to book, set up a Price Alert. We’ll track prices for you, and let you know when they rise or fall.
We crunched all the numbers in our flight calendar, and it looks like the cheapest time to book a flight to Santo Domingo is around 40 days in advance, so don’t leave your flight to the last minute.
In April, the average temperature is usually around 27°C. August is typically the warmest month in Santo Domingo, when it usually averages around 31°C. You can expect the least rain in March. The coldest month is January, with temperatures averaging 21°C. The rainiest month is September.
Currently, Arajet offers the cheapest flight tickets to Santo Domingo.

How to find cheap flights to Santo Domingo from Cartagena

Looking for cheap tickets from Cartagena to Santo Domingo? Here are a few tips on how to secure the best flight price and make your journey as smooth as possible.

  • Simply hit "search." From Delta Air Lines to international carriers like Emirates, we compare all major airlines along with the most popular online travel agents to find the cheapest plane tickets from Cartagena to Santo Domingo. And with us, there are no hidden fees – what you see is what you pay.
  • Compare flight deals to Santo Domingo from Cartagena from over 1,000 providers. Then choose the cheapest plane tickets or fastest journeys.
  • Flex your dates to find the best Cartagena–Santo Domingo ticket prices. If you're flexible when it comes to your travel dates, use Skyscanner's "Whole month" tool to find the cheapest month, and even day to fly to Santo Domingo from Cartagena.
  • Set up a Price Alert. You can easily track the fare of your cheap Cartagena–Santo Domingo flights by creating an alert. Whenever prices go down or up, you'll get an email or push notification to help make sure you get the best possible flight deal.
  • Fly without stops. Only interested in direct flights between Cartagena and Santo Domingo? Make sure to tick "Direct flights only" when performing a search. If there are direct flights available on the route, these will appear in the results.
  • Find the cheapest Business Class flights from Cartagena and Santo Domingo. We scour the Internet for the best Business, Premium Economy and First Class flight fares to Santo Domingo, too. Check the difference in price as you search – you might just stumble on a last-minute low fare. Note that not all cabin classes are available for every destination or airline.
  • Include nearby airports in your search. Widen your search for Cartagena to Santo Domingo flight deals by selecting the "add nearby airports" option. This will allow you to see flight prices for all the nearest airports at your departure point and your destination and could help you save the next time you travel.

    • Combine your flight to Santo Domingo from Cartagena with hotels and car rental

    Once you've secured your cheap flight ticket from Cartagena to Santo Domingo, discover the best prices and exclusive rates for hotels in Santo Domingo or nearby. You can also compare hundreds of car rental companies at once so you get the best car rental price for your trip.


Plan the rest of your trip from Cartagena to Santo Domingo

Prices shown on this page are estimated lowest prices only. Found in the last 45 days.